TPMT Sensitivity Test

TPMT Sensitivity Test

Polymorphisms in the thiopurine methyltransferase (TPMT) gene give rise to individual variations in the activity of the TPMT enzyme.

Reduced TPMT activity can lead to adverse patient reaction when treated with thiopurine drugs (occurring in 10-28% of patients receiving the treatment). These drugs are commonly prescribed across a range of disorders and disciplines that include: leukaemia, post-transplantation, dermatology, gastroenterology, rheumatology, and autoimmune diseases such as Crohn’s disease and lupus.

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NewGene Limited
Bioscience Building
International Centre for Life
Newcastle upon Tyne
NE1 4EP, UK

Tel: +44 (0)191 242 1923
Fax: +44 (0)191 241 8799
Email: info@newgene.org.uk

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Mon – Fri 08:30 to 17:00, closed Bank Holidays

An ISO 15189 accredited Medical Laboratory company

NewGene Limited | Company Number: 06735445

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