RASopathy Gene Panel

RASopathy gene panel

The NewGene RASopathy gene panel is a comprehensive diagnostic test for all Noonan spectrum disorders.

Based on next generation sequencing technology the RASopathy Test simultaneously screens all coding regions and splice sites of 15 genes for the mutations causative of all the RASopathy disorders. This comprehensive test replaces the current multi-stage strategy that is both time-consuming and costly and reduces the likelihood of missed molecular diagnosis.

PTPN11 BRAF SOS1 RAF1 KRAS HRAS NRAS SHOC2 CBL SPRED-1 MAP2K2 MAP2K2 RIT1 A2ML1 NF1
Noonan syndrome
Noonan-like syndrome disorder (NSLL)
Noonan-like syndrome with loose anagen hair (NSLH)
Cardio-facio-cutaneous syndrome (CFC)
Costello syndrome
LEOPARD syndrome (multiple lentigines syndrome)
Legius syndrome (Neurofibromatosis type 1-like syndrome)

Table shows the fifteen genes included in the NewGene Rasopathies panel and the implication of each gene in the different Noonan spectrum disorders.

Contact us

NewGene Limited
Bioscience Building
International Centre for Life
Newcastle upon Tyne
NE1 4EP, UK

Tel: +44 (0)191 242 1923
Fax: +44 (0)191 241 8799
Email: info@newgene.org.uk

Click here for location map

Mon – Fri 08:30 to 17:00, closed Bank Holidays

An ISO 15189 accredited Medical Laboratory company

NewGene Limited | Company Number: 06735445

Technology Partners

Agilent Technologies

Agena Bioscience

Illumina

Sophia Genetics

Qiagen

Promega

Enquiry form