Gastro-Intestinal Stromal Tumours

Gastro-Intestinal Stromal Tumours

Gastrointestinal stromal tumours (GIST) affect the connective and supportive tissues of the digestive tract or nearby structures within the abdomen. They are a rare cancer, accounting for approximately 2% of tumours in the gastrointestinal region and are highly resistant to chemotherapy. In many cases the cause is found to be activating mutations in the cKIT and PDGFRA genes. Clinical evidence demonstrates that mutation status can predict the patient response to tyrosine kinase inhibitors such as Imatinib.

Therefore, the identification of the genotype of the tumour can be used to confirm diagnosis, determine the appropriate treatment response and provide prognostic information.

Contact us

NewGene Limited
Bioscience Building
International Centre for Life
Newcastle upon Tyne
NE1 4EP, UK

Tel: +44 (0)191 242 1923
Fax: +44 (0)191 241 8799
Email: info@newgene.org.uk

Click here for location map

Mon – Fri 08:30 to 17:00, closed Bank Holidays

An ISO 15189 accredited Medical Laboratory company

NewGene Limited | Company Number: 06735445

Technology Partners

Agilent Technologies

Agena Bioscience

Illumina

Sophia Genetics

Qiagen

Promega

Enquiry form